Statin Allergy

In others side effects such as muscle pain or liver problems make it too hard to take statins.

Statin allergy. Some of these include. Bile acid sequestrants may decrease the effectiveness of some statins. Garlic oat bran artichoke barley sitostanol beta sitosterol blond psyllium. Certain factors may put you at an increased risk for statin intolerance.

The risk of very serious side effects is extremely low and calculated in a few cases per million people taking statins. The staff in the statin intolerance service will conduct a comprehensive cardiovascular evaluation to determine if your symptoms are due to statin intolerance or other conditions. If a statin doesn t help you that doesn t mean you re out of luck. The major statin induced adverse effects are muscle related complications myalgia myopathy rhabdomyolysis hepatotoxicity nephrotoxicity proteinuria headache rash and gastrointestinal discomforts 3 4 these adverse effects manifest more severely in patients aged over 80 years with liver and muscle disorders chronic renal insufficiency with diabetes or hypothyroidism or co prescription of agents that compete with statins for metabolism such as fibrates cyclosporine warfarin.

If your doctor diagnoses you with a different condition your doctor may refer you to another area within mayo clinic for treatment. Rhabdomyolysis can occur when you take statins in combination with certain drugs or if you take a high dose of statins. Nicotinic acid niacin in high doses greater than 1 gram a day could increase the risk of experiencing statin side effects. 2 either complete intolerant to any statin at any dose or partial intolerant to some statins at some.

The most common side effects reported with statins include. A headache belching or excessive gas constipation heartburn indigestion nausea or stomach discomfort hoarseness lower back or side pain muscle pain tenderness or weakness pain or tenderness around the eyes and cheekbones painful or. To avoid this it may be recommended to separate your statin dose and bile acid sequestrant dose by at least four hours. If appropriate drug withdrawal and rechallenge can strengthen this association.

Statin intolerance is a clinical syndrome that is.